S Series Sterilizable In Place Pilot Scale Bioreactors / Fermenters

The S series pilot scale bioreactors / fermenters are designed for research and development in process scale-up. Culture vessels from 5 to 200L.

S series Pilot Scale Bioreactors / Fermenters were designed with the intention to face all the problems related to scaling-up, from the laboratory to the production stage, with maximum easiness.

All fermenters/bioreactors of this series are compact and flexible (optionally on wheels) with the possibility to be installed even in limited spaces.

They are completely assembled and tested in the factory, these fermentation units are ready for installation at the user’s site.

The control system is based on a PLC and the SCADA supervisory Solaris SBC-16, and is designed to provide a high level of automated management of the fermentation processes. Installed on the Esedra up to the industrial ‘I’ series facilities the scaling-up procedures.

The system is in accordance with CFR 21 Part 11.

GMP Customized solutions: fully automated, strongly engineered to fulfill the customer’s need for compactness and operability.

Top quality stainless steel with excellent finishing, high technology and design. On line removable and sterilizable sensors permits their replacement during the process without compromising sterility.

Steam bridge diaphragm valves to guarantee sterility during inoculum, sampling, harvesting and feedings. Easy to access service lines for performing maintenance jobs without any difficulty.

The flexible installation of Solaris probes and accessories for media addition, aeration, sampling, harvesting, perfusion, load destruction, CIP, etc. is guaranteed with the standardized ports.

The modular design, in combination with the variety of proven accessories, enables the performance of biotechnological processes with enzymes, microorganisms, fungi, algae, plant or animal cells.

Our equipment fulfils the required national guidelines, ASME and cGMP/FDA-regulations (including IQ and OQ documentation on request).

  • Culture vessels from 5 L – 200 Liters
  • Instrumentation (including sensors) for control and measurement of pH, Eh, dO2, CO2, RPM, Gas Mixing, Temperature, Antifoam, Feeds SCADA Control System
  • Software management data – graphics designed for microbial and cell fermentation, for batch, fed-batch and continuous processes
  • Complete range of accessories
  • Mechanical or magnetic agitation system, fitted with a measurement and control system based on a PLC and the SCADA supervisor.

  • High quality, meets most sophisticated international standards
  • Microbial and cell fermentation, for batch, fed-batch and continuous processes
  • 100% customized solutions